They had a lower MV duration at a mean of 3.75 days ☑.8 SD. Successfully weaned and survivors represent 60% ( n = 24) of all patients included in this study. Lung mechanics (compliance and airway resistance), DSF, ETCO 2, and arterial blood gases were measured at the following times: on admission to the ICU, initially, and finally before extubation. Patients and methodsįorty consecutive patients admitted to the ICU with acute respiratory failure due to chronic obstructive lung diseases and acute severe asthma were enrolled in the study. The present study aimed to demonstrate the prognostic value of ventilatory parameters including that of the dead-space fraction (DSF), end-tidal carbon dioxide (ETCO 2), lung mechanics, and gas exchange during the application of MV. MV is an integral part of the treatment for acute respiratory failure. From the pathophysiological standpoint, they have increased airway resistance, pulmonary hyperinflation, and high pulmonary dead space, leading to an increased work of breathing. Patients with obstructive air flow including chronic obstructive lung diseases and bronchial asthma use a substantial proportion of mechanical ventilation (MV) in the ICU, and their overall mortality with ventilator support can be significant.
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